Basic Information   [Help]    back to top..
Gene ID AT3G26790
Gene Name FUS3
Gene Alias FUSCA 3
Gene Type protein_coding
Description FUSCA 3 (FUS3); CONTAINS InterPro DOMAIN/s: Transcriptional factor B3 (InterPro:IPR003340); BEST Arabidopsis thaliana protein match is: AP2/B3-like transcriptional factor family protein (TAIR:AT3G24650.1); Has 875 Blast hits to 861 proteins in 60 species: Archae - 0; Bacteria - 0; Metazoa - 1; Fungi - 7; Plants - 523; Viruses - 0; Other Eukaryotes - 344 (source: NCBI BLink).
 
GO Information   [Help] back to top
Gene IDAT3G26790
GO IDOntologyGO term
GO:0003677FunctionDNA binding
GO:0003677FunctionDNA binding
GO:0003700Functiontranscription factor activity
GO:0016563Functiontranscription activator activity
GO:0009733Processresponse to auxin stimulus
GO:0009793Processembryonic development ending in seed dormancy
GO:0009793Processembryonic development ending in seed dormancy
GO:0010116Processpositive regulation of abscisic acid biosynthetic process
GO:0010262Processsomatic embryogenesis
GO:0010362Processnegative regulation of anion channel activity by blue light
 
UniGene Information   [Help] back to top
Gene IDAT3G26790
UniGene IDAt.6029
Express Tissueseed| silique
Gene IDAT3G26790
UniGene IDAt.66989
Express Tissueseed
 
Expression Profile   [Help][Sample Description] back to top
 
Gene Structure   [Help] back to top
Gene Orientation: -           Gene Length: 2162
Gene Position on Chromosome: Start: 9853828     End: 9855989
UTR Position : AT3G26790.1: 1-241 1966-2162
Coding Region: AT3G26790.1: 242-484 676-765 848-948 1272-1318 1421-1497 1582-1965
 
Protein Domain Information   [Help] back to top
Model ID: AT3G26790.1 Model Length: 314
PositionPfam DomainPfam IDScoreE-value
91-196B3PF02362101.43.9e-30
 
Mutant Information   [Help] back to top
Gene IDAT3G26790
Mutant Namefus3-3
TAIR Stock NoTAIR Accession NoMutagen
CS80141005161550ethylmethane sulfonate
Stock Description 
Phenotype"accumulation of anthocyanin in developing embryos; seeds desiccation sensitive; seeds germinate and leaf primordia appear before desiccation; cotyledons have trichomes and have both cotyledon and leaf characteristics; dry seed shrunken and does not germinate; some similar phenotypic characteristics to, but not allelic to, leafy cotyledon (lec1, lec2); conditional lethal."
Gene IDAT3G26790
Mutant Namefus3-8
TAIR Stock NoTAIR Accession NoMutagen
CS61281005833106gamma rays
Stock Description 
PhenotypeDefective in late embryo development and germination; immature embryos enter germinative development and the shoot apical meristems develop leaf primordia before seed desiccation begins; desiccation intolerant; reduced seed dormancy; reduced seed storage protein levels; increased accumulation of anthocyanins in the cotyledons and reduced chlorophyll content; cotyledons bear trichomes and their ultrastructure is similar to that of leaf primordia; germination is inhibited by exogenous ABA; heterozygous adult plants are indistinguishable from wt plants.
Gene IDAT3G26790
Mutant Namefus3-8
TAIR Stock NoTAIR Accession NoMutagen
CS61291005833107gamma rays
Stock Description"originally isolated in Columbia background (Col), subsequently backcrossed 3 times to Landsberg erecta (Ler) to obtain the fus3-8/Ler line." 
PhenotypeDefective in late embryo development and germination; immature embryos enter germinative development and the shoot apical meristems develop leaf primordia before seed desiccation begins; desiccation intolerant; reduced seed dormancy; reduced seed storage protein levels; increased accumulation of anthocyanins in the cotyledons and reduced chlorophyll content; cotyledons bear trichomes and their ultrastructure is similar to that of leaf primordia; germination is inhibited by exogenous ABA; heterozygous adult plants are indistinguishable from wt plants
 
Publication   [Help] back to top
Vicient CM, Bies-Etheve N, Delseny M. 2000. Changes in gene expression in the leafy cotyledon1 (lec1) and fusca3 (fus3) mutants of Arabidopsis thaliana L. J Exp Bot. 51(347): 995-1003 [Abstract][PubMed ID: 10948227]

Riechmann JL, Heard J, Martin G, Reuber L, Jiang C, Keddie J, Adam L, Pineda O, Ratcliffe OJ, Samaha RR, Creelman R, Pilgrim M, Broun P, Zhang JZ, Ghandehari D, Sherman BK, Yu G. 2000. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Science. 290(5499): 2105-10 [Abstract][PubMed ID: 11118137]

Brocard-Gifford IM, Lynch TJ, Finkelstein RR. 2003. Regulatory networks in seeds integrating developmental, abscisic acid, sugar, and light signaling. Plant Physiol. 131(1): 78-92 [Abstract][PubMed ID: 12529517]

Kroj T, Savino G, Valon C, Giraudat J, Parcy F. 2003. Regulation of storage protein gene expression in Arabidopsis. Development. 130(24): 6065-73 [Abstract][PubMed ID: 14597573]

Baumbusch LO, Hughes DW, Galau GA, Jakobsen KS. 2004. LEC1, FUS3, ABI3 and Em expression reveals no correlation with dormancy in Arabidopsis. J Exp Bot. 55(394): 77-87 [Abstract][PubMed ID: 14676287]

Monke G, Altschmied L, Tewes A, Reidt W, Mock HP, Baumlein H, Conrad U. 2004. Seed-specific transcription factors ABI3 and FUS3: molecular interaction with DNA. Planta. 219(1): 158-66 [Abstract][PubMed ID: 14767767]

Gazzarrini S, Tsuchiya Y, Lumba S, Okamoto M, McCourt P. 2004. The transcription factor FUSCA3 controls developmental timing in Arabidopsis through the hormones gibberellin and abscisic acid. Dev Cell. 7(3): 373-85 [Abstract][PubMed ID: 15363412]

Curaba J, Moritz T, Blervaque R, Parcy F, Raz V, Herzog M, Vachon G. 2004. AtGA3ox2, a key gene responsible for bioactive gibberellin biosynthesis, is regulated during embryogenesis by LEAFY COTYLEDON2 and FUSCA3 in Arabidopsis. Plant Physiol. 136(3): 3660-9 [Abstract][PubMed ID: 15516508]

Kagaya Y, Toyoshima R, Okuda R, Usui H, Yamamoto A, Hattori T. 2005. LEAFY COTYLEDON1 controls seed storage protein genes through its regulation of FUSCA3 and ABSCISIC ACID INSENSITIVE3. Plant Cell Physiol. 46(3): 399-406 [Abstract][PubMed ID: 15695450]

Kagaya Y, Okuda R, Ban A, Toyoshima R, Tsutsumida K, Usui H, Yamamoto A, Hattori T. 2005. Indirect ABA-dependent regulation of seed storage protein genes by FUSCA3 transcription factor in Arabidopsis. Plant Cell Physiol. 46(2): 300-11 [Abstract][PubMed ID: 15695463]

Gaj MD, Zhang S, Harada JJ, Lemaux PG. 2005. Leafy cotyledon genes are essential for induction of somatic embryogenesis of Arabidopsis. Planta. 222(6): 977-88 [Abstract][PubMed ID: 16034595]

To A, Valon C, Savino G, Guilleminot J, Devic M, Giraudat J, Parcy F. 2006. A network of local and redundant gene regulation governs Arabidopsis seed maturation. Plant Cell. 18(7): 1642-51 [Abstract][PubMed ID: 16731585]

Tsukagoshi H, Morikami A, Nakamura K. 2007. Two B3 domain transcriptional repressors prevent sugar-inducible expression of seed maturation genes in Arabidopsis seedlings. Proc Natl Acad Sci U S A. 104(7): 2543-7 [Abstract][PubMed ID: 17267611]

Wang H, Guo J, Lambert KN, Lin Y. 2007. Developmental control of Arabidopsis seed oil biosynthesis. Planta. 226(3): 773-83 [Abstract][PubMed ID: 17522888]

W-K Ng D, Hall TC. 2008. PvALF and FUS3 activate expression from the phaseolin promoter by different mechanisms. Plant Mol Biol. 66(3): 233-44 [Abstract][PubMed ID: 18038114]

Tiedemann J, Rutten T, Monke G, Vorwieger A, Rolletschek H, Meissner D, Milkowski C, Petereck S, Mock HP, Zank T, Baumlein H. 2008. Dissection of a complex seed phenotype: novel insights of FUSCA3 regulated developmental processes. Dev Biol. 317(1): 1-12 [Abstract][PubMed ID: 18343361]

Santos-Mendoza M, Dubreucq B, Baud S, Parcy F, Caboche M, Lepiniec L. 2008. Deciphering gene regulatory networks that control seed development and maturation in Arabidopsis. Plant J. 54(4): 608-20 [Abstract][PubMed ID: 18476867]

Parcy F, Valon C, Kohara A, Misera S, Giraudat J. 1997. The ABSCISIC ACID-INSENSITIVE3, FUSCA3, and LEAFY COTYLEDON1 loci act in concert to control multiple aspects of Arabidopsis seed development. Plant Cell. 9(8): 1265-77 [Abstract][PubMed ID: 9286105]

Luerssen H, Kirik V, Herrmann P, Misera S. 1998. FUSCA3 encodes a protein with a conserved VP1/AB13-like B3 domain which is of functional importance for the regulation of seed maturation in Arabidopsis thaliana. Plant J. 15(6): 755-64 [Abstract][PubMed ID: 9807814]

 
Sequence   [Help] back to top
AT3G26790.1
CDS sequence   Protein sequence   cDNA sequence   Genomic sequence